Cytoplasmic retention signal

WebNov 12, 2004 · Here we report that the cytoplasmic localization of hHDAC6 is resistant to treatment with leptomycin B (LMB), demonstrate that the SE14 repeat domain is responsible for this resistance, and show that hHDAC6 possesses intrinsic … WebMar 14, 2024 · The retention signal is recognized by specific receptors present in the ER and cis-GA, which retrieve the protein from post-ER compartments and return them to …

The Pest-Like Sequence of IκBα Is Responsible for Inhibition of …

WebSep 1, 1994 · Although the cytoplasmic retention signal region is outside the cyclin box, its sequence is well conserved in human cyclin B2, and is both necessary and sufficient to keep cyclin B2 in the cytoplasm. WebJun 20, 2000 · The IRF3 protein has a nuclear export signal (NES) specifying its cytoplasmic retention . Examination of the p48 protein primary amino acid sequence … description of a builder https://footprintsholistic.com

Frontiers Sequence Determinants for Nuclear Retention and …

WebMar 21, 2008 · We have determined that the molecular basis for this specialized property of hA3G is a novel cytoplasmic retention signal (CRS) that is necessary and sufficient to restrict wild-type hA3G and chimeric constructs to the cytoplasm. WebOct 19, 2005 · Distribution of YB-1 between the nucleus and the cytoplasm is known to be dependent on nuclear targeting and cytoplasmic retention signals located within the C-terminal portion of YB-1. WebApr 8, 2014 · When present within 4-residues of the TMD it serves as a Golgi export signal, but when located at the C-terminus of the 68-residue p14 cytoplasmic endodomain it functions as an ER retention signal. The PBM has no effect on protein trafficking when located at an internal position in the cytoplasmic domain. description of a building on fire

Regulation of protein secretion through chemical

Category:The M-PMV cytoplasmic targeting-retention signal directs …

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Cytoplasmic retention signal

Transportin-2 plays a critical role in nucleocytoplasmic ... - Nature

WebJul 18, 2008 · The cytoplasmic tails play a role in the localization of glycosyltransferases, and coat protein complex I (COPI) vesicle–mediated retrograde transport is also involved … WebCRS - Cytoplasmic Retention Signal. MRI Magnetic Resonance Imaging. CT Computed Tomography. PCR Polymerase Chain Reaction. HIV Human Immunodeficiency Virus. …

Cytoplasmic retention signal

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WebThe ER retention signal of the cytoplasmic domain could not be localized to a single amino acid segment by deletion analysis. These results show that cytochrome P450 2C2 … WebAug 1, 1999 · studies provide evidence for a cytoplasmic targeting/retention signal (CTRS) in MA that is responsible for intracytoplasmic capsid assembly in Type D retroviruses.

WebAug 1, 1997 · Although JNK is located in both the cytoplasm and the nucleus of quiescent cells, activation of JNK is associated with accumulation of JNK in the nucleus ( 8 ). … WebCytosolic retention of phosphorylated extracellular signal-regulated kinase and a Rho-associated kinase-mediated signal impair expression of p21(Cip1/Waf1) in phorbol 12 …

WebJan 12, 2024 · The cytoplasmic tail is still not well known but contains an ER retrieval signal that is shared by other similar viruses. ... of the cell by as yet unknown retention … WebJul 15, 2004 · In fact, the nucleolar retention signal of human T cell leukemia virus type I protein p27 x-III and the HIV-Tat protein are also highly positively charged (Siomi et al., …

WebThe N- terminal signal/anchor of cytochrome P450 2C1 functioned as an ER retention signal when placed at the N terminus of several reporter proteins but not when fused at the C terminus of the extracellular domain of epidermal growth factor receptor, with or without a heterologous cytoplasmic domain.

WebMay 17, 2005 · Nucleocytoplasmic Shuttling with Periods of Retention: Smads Smad proteins are a family of inducible transcription factors that mediate signals from the transforming growth factor–β (TGF-β) superfamily of ligands, including TGF-β and bone morphogenetic protein (BMP). chs heart failureWebDec 7, 2024 · Combined with the genetic and microscope-based approaches, two types of the functionally coupled and evolutionally conserved localization regulatory motifs are identified, including the... chs heatingWebJul 11, 2013 · N-terminal deletions (Δ2–41 and Δ2–109) destroyed the cytoplasmic retention signal. Thus, SAMHD1K11A is cytoplasmic, yet SAMHD1 (Δ2–41 and Δ2–109) mutants could still be detected in the … c h shear \u0026 sonsWebNov 6, 2024 · In this study, we identified that the glycophorin transmembrane domain encoded an ER/Golgi retention signal, which could be counteracted by forward-trafficking signals (i.e., the R18 epitope of GPA/GP.Mur; the cytoplasmic domain of GPA ) … description of a burnWebOct 29, 2024 · Our results also show that Transportin-2 (TNPO2, importin-3) enhances the cytoplasmic localisation of ERα, not as a nuclear export receptor, but rather as a cytoplasmic retention factor, while it ... description of a bull snakeWebNational Center for Biotechnology Information description of a busy placeWebMar 30, 2024 · The Pest-Like Sequence of IκBα Is Responsible for Inhibition of DNA Binding but Not for Cytoplasmic Retention of c-Rel or RelA Homodimers. Mary K. Ernst Laboratory of Molecular ... suggesting that it may perform the same function in cells when the activating signal is no longer present. Structurally, the human I κ Bα molecule can be divided ... description of a bunny